Basement membrane (BM) proteoglycans are more than charged filtering agents. These complex macromolecules can direct cell responses by a wide range of sophisticated mechanisms. BM proteoglycans are ...
LA JOLLA, CA—Scientists at Scripps Research have developed a set of methods for the closer study of one of the least-accessible, least-understood players in biology: protein-sugar conjugates called ...
Proteoglycans—molecules consisting of a core protein with multiple sugar chains—are so complex that researchers usually study the protein and sugar components separately, which makes it difficult to ...
In a recent study published in IScience, a team of researchers from the United States examined the impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways ...
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