Generally, the dual NRTI backbone treatment of combination with a non-NRTI (NNRTI) or protease inhibitor (PI) should comprise a cytidine analogue (lamivudine, emtricitabine) and a thymidine analogue ...
Comparison of Outcomes After Fluorouracil-Based Adjuvant Therapy for Stages II and III Colon Cancer Between 1978 to 1995 and 1996 to 2007: Evidence of Stage Migration From the ACCENT Database Although ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, No. 22, [Part 1: Biological Sciences] (Nov. 15, 1984), pp. 7051-7055 (5 pages) ...
A vascular dilatation in the aorta can be life-threatening if it bursts. These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the ...
Pathogen recognition is based on the presence of Toll-like receptors (TLRs), which detect pathogen-associated molecular patterns (PAMPs) to coordinate the immune cascade. These receptors are encoded ...
The discovery of ArcS, which can utilize a nucleoside as a minimum substrate, provides new insights into the synthesis of precursor molecules for these modified nucleosides. The results of this ...
Clin Drug Invest. 2007;27(8):509-531. Because of its poor tolerability, regimen complexity and drug-interaction potential relative to other new NRTIs, use of didanosine has decreased over the last few ...
In a study published in Genome Research, a team of researchers, including Cornell College Assistant Professor of Biology Sophie Gillett, looked at regions of human genetic code that are known for ...