Among modern cancer therapies, immune checkpoint inhibitors (ICI) are among the most successful treatment methods. These ...

In the lab, it’s easier to grow simple balls of cells than complex asymmetrical structures with two distinct ends—like the one million filtering units, or nephrons, that make up a human kidney. But ...

CD45 + C1q + CCR8+ cells may serve as a biomarker for kidney disease severity and progression risk, reflecting inflammation and fibrosis. Elevated levels of these cells correlate with serum creatinine ...

MHH researchers discover sugar structures on kidney cells that can predict response to treatment with immune checkpoint inhibitors.

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Cancer-fighting T-cells, the immune system's primary enforcers, are scarce in the rare kidney cancer called chromophobe renal cell carcinoma (ChRCC) and those that are present are indifferent to the ...