Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at ...

The global challenge posed by HIV-1 infection continues to drive research into its underlying mechanisms and the host immune response. Central to this pursuit is the role of T cells, particularly CD4 ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating-and possibly even curing-the disease a seemingly insurmountable obstacle to achieve. But ...

May 2, 2012 — Gene transfer using a retroviral vector that directs a patient's T cells to recognize HIV appears to be safe and persistent, according to a study published May 2 in Science Translational ...

A single center letter describes lung transplantation in people living with HIV despite CD4 counts under 200 during evaluation, emphasizing prior viral suppression and clinical context when assessing ...

Led by a team of African researchers, first doses of the novel T cell-inducing GRAdHIVNE1 vaccine candidate have been given. HARARE, ZIMBABWE, ROME, ITALY, NEW YORK, NY, AND CAMBRIDGE, MA / ACCESS ...

– New grant from the Bill & Melinda Gates Foundation supports the Phase 1 development of VIR-1388, an investigational HIV T cell vaccine based on a novel vector – – Long-standing partnership further ...

Scientists have identified a natural human protein that can rouse dormant HIV inside infected cells, a finding that sharpens one of the most promising paths toward a cure. By showing that the virus’s ...